The Alumni

David Medovoy, PhD

Beachwood, OH

University of Chicago, PhD 2013

Dual Mentors: Benoît Roux, Eduardo Perozo

Thesis Title

I study the dynamics of potassium channels using Molecular Dynamics simulations and spectroscopic techniques.

Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway
T Ferrer, Julio F Cordero-Morales, M Arias, Eckhard Ficker, David Medovoy, Eduardo Perozo, Martin Tristani-Firouzi
J Biol Chem. 2011 Nov 11;286(45):39091-9. PMC3234734

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Qufei Li, Sherry Wanderling, Marcin Paduch, David Medovoy, Carlos Villalba-Galea, Raymond Hulse, Benoit Roux, Anthony Kossiakoff and Eduardo Perozo
Nat Struct Mol Biol. 2014 Mar;21(3):244-52. doi: 10.1038/nsmb.2768. Epub 2014 Feb 2.

A repulsion mechanism explains magnesium permeation and selectivity in CorA.
Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E.
Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3002-7. doi: 10.1073/pnas.1319054111. Epub 2014 Feb 10.

The Graduate Program in Biophysical Sciences

The Alumni

David Medovoy, PhD

Thesis Title

I study the dynamics of potassium channels using Molecular Dynamics simulations and spectroscopic techniques.

Abstract