Use of chemoproteomics to characterize and selectively modulate protein‒ligand and protein‒ protein interactions in normal and diseased biological settings.
University of Arizona, B.S., 2005
Harvard University, Ph.D., 2010
The Scripps Research Institute, Postdoctoral Fellow, 2011-2014
Who we are: The Moellering Lab is a multi-disciplinary group of scientists with training in chemistry, biochemistry, cell biology and mass spectrometry. We are uniquely situated in both the Department of Chemistry and the Institute for Genomics and Systems Biology at the University of Chicago - thus figuratively and physically bridging the physical and biological sciences.
What we do: Research in the Moellering Lab lies at the interface of chemistry and biology, with an eye towards understanding and intervening in human disease. By integrating chemical synthesis, cell biology and mass spectrometry platforms, our research aims to identify novel biological mechanisms underlying diseases such as diabetes and cancer, and to subsequently develop innovative diagnostic and therapeutic modalities to impact these disorders. We are specifically interested in developing new chemical tools and technologies to study complexity and dynamics in the proteome, thus enabling targeted manipulation of protein targets and the pathways they govern.